BDBM50036600 CHEMBL3354262
SMILES CN1C(=N)N[C@](CCC2CCCCC2)(C[C@H]2CCC[C@H](C2)NC(=O)Nc2ccc3ccccc3n2)C1=O
InChI Key InChIKey=HAYVUYMTLMAYFA-WMEWVQGBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50036600
Affinity DataKi: 22nMAssay Description:Inhibition of purified human BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nMAssay Description:Inhibition of cathepsin-D (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 258nMAssay Description:Inhibition of BACE1-mediated amyloid beta 40 production in HEK293-APPswe/lon cells by whole cell assayMore data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Inhibition of BACE1-mediated amyloid beta 40 production in HEK293-APPswe/lon cells by whole cell assay in presence of P-gp inhibitorMore data for this Ligand-Target Pair