BDBM50036750 2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)heptyloxy]phenol; with sodium ion::CHEMBL48667::Sodium salt of 2-Ethoxy-4-ethyl-5-[6-methyl-6-(2H-tetrazol-5-yl)-heptyloxy]-phenol::sodium 2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)heptyloxy]phenol

SMILES CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[n-]n2)cc1O

InChI Key InChIKey=QDWLZEFMYHPCCB-UHFFFAOYSA-N

Data  5 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50036750   

TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity of the compound against human neutrophil Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataKi:  14nMAssay Description:Binding affinity of the compound against Guinea pig membrane LTB4 Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataKi:  14nMAssay Description:Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataKi:  14nMAssay Description:Inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataKi:  14nMAssay Description:In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataIC50:  206nMAssay Description:Inhibition of LTB4-induced human neutrophil CD11b/CD18 integrin up-regulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataIC50:  4.80nMAssay Description:In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataIC50:  206nMAssay Description:Inhibition of LTB4-induced CD11b/CD18 integrin up-regulation in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataIC50:  206nMAssay Description:Binding affinity of the compound against human neutrophil Receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50036750(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Affinity DataIC50:  4.80nMAssay Description:Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assayMore data for this Ligand-Target Pair
In DepthDetails Article