BDBM50037134 (+)-trans-3-Cyclopropylmethyl-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinolin-9-ol::(+/-)-trans-3-Cyclopropylmethyl-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinolin-9-ol::(-)-trans-3-Cyclopropylmethyl-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinolin-9-ol::(4aR,7aS,12bS)-3-Cyclopropylmethyl-2,3,4,4a,5,6,7,7a-octahydro-1H-8-oxa-3-aza-benzo[d]fluoren-9-ol::CHEMBL104042
SMILES Oc1cccc2c1O[C@H]1CCC[C@H]3CN(CC4CC4)CC[C@]213
InChI Key InChIKey=SQZBAUUHDXMUTO-FNHZYXHNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50037134
Affinity DataKi: 0.0800nMAssay Description:Displacement of [125I]OXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [125I]OXY from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [125I]OXY from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:In vivo binding affinity against mu opioid receptor was measured by using labeled ligand [3H]-Naloxone (0.5 nM)More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:In vivo binding affinity against kappa opioid receptor was measured by using labeled ligand [3H]-ethylketocyclazocine (1 nM) with 500 nM DADLE and 20...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]OXY from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:In vivo binding affinity against delta Opioid receptor was measured by using labeled ligand [3H]-DADLE (1 nM) with 4 nM sufentanilMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:In vivo binding affinity against sigma Opioid receptor was measured by using labeled ligand [3H]-SKF- 10,047 (1 nM)More data for this Ligand-Target Pair
Affinity DataKi: 201nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 201nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Partial agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS binding after 3 hrs by liqu...More data for this Ligand-Target Pair
Affinity DataKd: 0.220nMAssay Description:Binding affinity to human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding affinity to human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair