BDBM50037501 CHEMBL1170408
SMILES CCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)c1ccc(Oc2cc(nc3cc(OC)ccc23)-c2ccccc2)c(C=C)c1)C(=O)NS(=O)(=O)CCCC=C
InChI Key InChIKey=VEKPHSPAMHKHOX-QDXXHNKASA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50037501
Affinity DataKi: 63nMAssay Description:Inhibition of HCV genotype 1a NS3/4A protease using Ac-DED(Edans)EEAbu-psi[COO]ASK(Dabcyl)-NH2 as substrate by FRET assayMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Inhibition of HCV NS3 protease D168V mutant by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Inhibition of HCV NS3 protease A156T mutant by FRET assayMore data for this Ligand-Target Pair