BDBM50037870 CHEMBL333718::[(3R,5R)-2-Oxo-5-phenyl-3-(3-m-tolyl-ureido)-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl]-acetic acid tert-butyl ester

SMILES Cc1cccc(NC(=O)N[C@@H]2C[C@H](c3ccccc3)c3ccccc3N(CC(=O)OC(C)(C)C)C2=O)c1

InChI Key InChIKey=CLMCTKVZMVJCQP-JWQCQUIFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037870   

TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037870(CHEMBL333718 | [(3R,5R)-2-Oxo-5-phenyl-3-(3-m-toly...)
Affinity DataIC50:  2.5nMAssay Description:In vitro affinity to the cholecystokinin type B receptor in guinea pig cortex assayed using [125I]-BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037870(CHEMBL333718 | [(3R,5R)-2-Oxo-5-phenyl-3-(3-m-toly...)
Affinity DataIC50:  50nMAssay Description:In vitro binding affinity for the cholecystokinin type A receptor in guinea pig pancreas assayed using [125I]-BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed