BDBM50037973 (R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2-(naphthalene-2-sulfonylamino)-3-phenyl-propionamide; hydrochloride::CHEMBL544830

SMILES NC(=N)N1CCC[C@@H](CNC(=O)[C@@H](Cc2ccccc2)NS(=O)(=O)c2ccc3ccccc3c2)C1

InChI Key InChIKey=WWJJOLLOSVQTGQ-GBXCKJPGSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50037973   

TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037973((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  32nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037973((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  47nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037973((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  2.60E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037973((R)-N-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-2...)
Affinity DataKi:  4.20E+4nMAssay Description:In vitro binding affinity by measuring the inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed