BDBM50038168 7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinolin-2-one::7-chloro-4-hydroxy-3-(3-phenoxyphenyl)quinolin-2(1H)-one::CHEMBL31741::L-701324
SMILES Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12
InChI Key InChIKey=FLVRDMUHUXVRET-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50038168
Affinity DataKi: 1nMAssay Description:Inhibition of [3H]glycine to glycine binding site, associated with the N-methyl-D-aspartate glutamate receptor 1 in crude synaptic membranes prepared...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of Escherichia coli AmpC beta lactamase using relaxed assay conditions in presence of 0.00001% Triton X-100 detergentMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+5nMAssay Description:Aggregate based-inhibition of Escherichia coli AmpC beta lactamase using stringent assay conditions in presence of 0.01% Triton X-100 detergentMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Compound was evaluated for its ability to displace [3H]-L-689,560 from rat cortical membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair