BDBM50038205 5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-benzoic acid methyl ester::CHEMBL131653

SMILES COC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O

InChI Key InChIKey=NOFICVMLKCZZHJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50038205   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50038205(5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-benzoic ac...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of EGF-stimulated DNA synthesis in ER22 cells, by measuring [3H]Me-dT incorporation into ER 22 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50038205(5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-benzoic ac...)
Affinity DataIC50:  600nMAssay Description:Inhibitory potency against protein tyrosine kinase activity associated with EGFR was evaluated using ER 22 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50038205(5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-benzoic ac...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of EGF-dependent DNA synthesis in ER 22 cells incubated with [3H]-TdRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50038205(5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-benzoic ac...)
Affinity DataIC50:  2.44E+4nMAssay Description:Inhibition of EGF-R Tyrosine kinase (TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50038205(5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-benzoic ac...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of EGFR(epidermal growth factor receptor) autophosphorylation in ER22 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed