BDBM50038263 2-Amino-8-propyl-2,8-dihydro-3H-pyrido[2,3-d]pyrimidin-4-one::CHEMBL135811
SMILES CCCN1C=CC=C2C(=O)NC(N)N=C12
InChI Key InChIKey=GMLQXCJLQFOMRX-UHFFFAOYSA-N
Data 11 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50038263
Affinity DataKd: 4.00E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
Affinity DataKd: 5.80E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with human dihydrofolate reductase using equations 11 a...More data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductaseusing equations 15 a...More data for this Ligand-Target Pair
Affinity DataKd: 830nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductaseusing equation 11More data for this Ligand-Target Pair
Affinity DataKd: 20.7nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with human dihydrofolate reductase using equation 4More data for this Ligand-Target Pair
Affinity DataKd: 6.50E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with human dihydrofolate reductase using equation 11More data for this Ligand-Target Pair
Affinity DataKd: 1.20E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
Affinity DataKd: 2.60nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductaseusing equation 4More data for this Ligand-Target Pair
Affinity DataKd: 2.10E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with human dihydrofolate reductase using equation 16More data for this Ligand-Target Pair
Affinity DataKd: 1.80E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair