BDBM50038276 (R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::7-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL110239

SMILES CCCN(C\C=C\I)C1CCc2ccc(O)cc2C1

InChI Key InChIKey=RTMIJLQPWFKAFE-FPYGCLRLSA-N

Data  9 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50038276   

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Affinity DataKi:  0.990nMAssay Description:Tested for binding affinity against dopamine receptor D3 expressed in Sf9 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Affinity DataKi:  1.85nMAssay Description:Tested for the inhibitory activity against Dopamine D3 receptor in infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Affinity DataKi:  1.90nMAssay Description:Tested for inhibition of the binding of [125I]NCQ298 to dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Affinity DataKi:  3.20nMAssay Description:Tested for the inhibitory activity against sigma receptor rat cerebellarMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [125I]trans-8-OH-PIPAT in membrane homogenates of hippocampal tissue ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Affinity DataKi:  5.10nMAssay Description:Tested for the inhibitory activity against 5-hydroxytryptamine 1A receptor in rat hippocampalMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Affinity DataKi:  6.60nMAssay Description:Tested for the inhibitory activity against D2H (high-affinity states) receptor in infected HEK 293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Affinity DataKi:  265nMAssay Description:Tested for inhibition of the binding of [125I]NCQ298 to D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Affinity DataKi:  265nMAssay Description:Tested for the inhibitory activity against Dopamine D2 receptor in infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Affinity DataKd:  0.480nMAssay Description:Binding affinity was tested against dopamine receptor D3 in rat striatal membarane homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50038276((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...)
Affinity DataKd:  0.130nMAssay Description:Binding affinity was tested against dopamine receptor D3 in the absence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed