BDBM50038287 CHEMBL135387::N-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-benzamide

SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccn2)CC1)c1ccccc1

InChI Key InChIKey=MNTHFSDLZXHALL-AQYVVDRMSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50038287   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50038287(CHEMBL135387 | N-{4-[2-(4-Pyridin-2-yl-piperazin-1...)
Affinity DataEC50:  4.90nMAssay Description:In vitro inhibition of forskolin-stimulated cAMP accumulation in GH4C1 cells transfected with the human Dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50038287(CHEMBL135387 | N-{4-[2-(4-Pyridin-2-yl-piperazin-1...)
Affinity DataIC50:  443nMAssay Description:Binding affinity towards Dopamine D2 receptor from rat striatal membranes, using [3H]- spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed