BDBM50038473 CHEMBL3354844::US9216981, 18

SMILES Fc1ccc(NS(=O)(=O)c2ccoc2)c(F)c1Nc1ncccc1-c1ncnc2[nH]cnc12

InChI Key InChIKey=ACIXGVIVJZJKNT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50038473   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent
LigandPNGBDBM50038473(CHEMBL3354844 | US9216981, 18)
Affinity DataIC50:  1nMpH: 7.2 T: 2°CAssay Description:To check the B-Raf kinase inhibitory activity of the compounds of the present invention, the following experiments were conducted.(1) Serial Signalin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent
LigandPNGBDBM50038473(CHEMBL3354844 | US9216981, 18)
Affinity DataIC50:  1nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Medpacto

US Patent
LigandPNGBDBM50038473(CHEMBL3354844 | US9216981, 18)
Affinity DataEC50:  2nMT: 2°CAssay Description:To check the B-Raf cell activity inhibitory capability of the compounds of the present invention, the following experiments were conducted in A375P...More data for this Ligand-Target Pair
In DepthDetails US Patent