BDBM50038859 (4S)-2-[(4-bromo-2-fluorophenyl)methyl]-6-fluoro-2,3-dihydro-1H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'-tetrone::CHEMBL304880

SMILES Fc1ccc2C(=O)N(Cc3ccc(Br)cc3F)C(=O)[C@@]3(CC(=O)NC3=O)c2c1

InChI Key InChIKey=BMHZAHGTGIZZCT-IBGZPJMESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038859   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50038859((4S)-2-[(4-bromo-2-fluorophenyl)methyl]-6-fluoro-2...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed