BDBM50039094 6,7-Dimethoxy-3-phenylethynyl-quinoline::CHEMBL67059

SMILES COc1cc2cc(cnc2cc1OC)C#Cc1ccccc1

InChI Key InChIKey=FIWNVHIDDOMDBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50039094   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039094(6,7-Dimethoxy-3-phenylethynyl-quinoline | CHEMBL67...)
Affinity DataIC50: >2.00E+4nMAssay Description:Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039094(6,7-Dimethoxy-3-phenylethynyl-quinoline | CHEMBL67...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.02-0.05More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed