BDBM50039237 1-{3-[Tris-(4-methoxy-phenyl)-methoxy]-propyl}-piperidine-3-carboxylic acid::CHEMBL308391

SMILES COc1ccc(cc1)C(OCCCN1CCCC(C1)C(O)=O)(c1ccc(OC)cc1)c1ccc(OC)cc1

InChI Key InChIKey=YEECPDWLBQWZKU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50039237   

TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039237(1-{3-[Tris-(4-methoxy-phenyl)-methoxy]-propyl}-pip...)
Affinity DataIC50:  1.03E+5nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039237(1-{3-[Tris-(4-methoxy-phenyl)-methoxy]-propyl}-pip...)
Affinity DataIC50:  1.21E+5nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039237(1-{3-[Tris-(4-methoxy-phenyl)-methoxy]-propyl}-pip...)
Affinity DataIC50:  1.69E+5nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed