BDBM50039238 1-{2-[Bis-(4-fluoro-phenyl)-(4-methoxy-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acid::CHEMBL72499

SMILES COc1ccc(cc1)C(OCCN1CCCC(C1)C(O)=O)(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=GWNRSBOBHVFWSC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039238   

TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039238(1-{2-[Bis-(4-fluoro-phenyl)-(4-methoxy-phenyl)-met...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039238(1-{2-[Bis-(4-fluoro-phenyl)-(4-methoxy-phenyl)-met...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039238(1-{2-[Bis-(4-fluoro-phenyl)-(4-methoxy-phenyl)-met...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039238(1-{2-[Bis-(4-fluoro-phenyl)-(4-methoxy-phenyl)-met...)
Affinity DataIC50:  1.51E+5nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed