BDBM50039242 1-{2-[Bis-(4-chloro-phenyl)-(4-methoxy-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acid::CHEMBL269439

SMILES COc1ccc(cc1)C(OCCN1CCCC(C1)C(O)=O)(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=HSSYPZBJVLXPLH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039242   

TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039242(1-{2-[Bis-(4-chloro-phenyl)-(4-methoxy-phenyl)-met...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039242(1-{2-[Bis-(4-chloro-phenyl)-(4-methoxy-phenyl)-met...)
Affinity DataIC50:  8.80E+4nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039242(1-{2-[Bis-(4-chloro-phenyl)-(4-methoxy-phenyl)-met...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039242(1-{2-[Bis-(4-chloro-phenyl)-(4-methoxy-phenyl)-met...)
Affinity DataIC50:  1.22E+5nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed