BDBM50039248 (R)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acid::CHEMBL419823

SMILES COc1ccc(cc1)C(OCCN1CCC[C@H](C1)C(O)=O)(c1ccc(OC)cc1)c1ccc(OC)cc1

InChI Key InChIKey=VDLDUZLDZBVOAS-JOCHJYFZSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50039248   

TargetSodium- and chloride-dependent betaine transporter(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039248((R)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-...)
Affinity DataIC50:  6.30E+5nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Rat)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039248((R)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-...)
Affinity DataIC50:  2.40E+5nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039248((R)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-...)
Affinity DataIC50:  8.60E+4nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50039248((R)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-...)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of mouse GTA4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50039248((R)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-...)
Affinity DataIC50:  8.51E+4nMAssay Description:Inhibition of mouse GTA 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50039248((R)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-...)
Affinity DataIC50:  2.75E+6nMAssay Description:Inhibition of mouse GTA 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50039248((R)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-...)
Affinity DataIC50:  5.13E+3nMAssay Description:Inhibition of mouse GTA 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039248((R)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-...)
Affinity DataIC50:  4.39E+5nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed