BDBM50039253 1-{2-[Tris-(4-fluoro-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acid::CHEMBL77423

SMILES OC(=O)C1CCCN(CCOC(c2ccc(F)cc2)(c2ccc(F)cc2)c2ccc(F)cc2)C1

InChI Key InChIKey=GTKDQZXNADEHML-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039253   

TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039253(1-{2-[Tris-(4-fluoro-phenyl)-methoxy]-ethyl}-piper...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039253(1-{2-[Tris-(4-fluoro-phenyl)-methoxy]-ethyl}-piper...)
Affinity DataIC50:  6.74E+6nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039253(1-{2-[Tris-(4-fluoro-phenyl)-methoxy]-ethyl}-piper...)
Affinity DataIC50:  1.27E+6nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50039253(1-{2-[Tris-(4-fluoro-phenyl)-methoxy]-ethyl}-piper...)
Affinity DataIC50:  3.67E+6nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed