BDBM50039655 5,7-Dimethoxy-3-pyridin-4-yl-quinoline::CHEMBL68423

SMILES COc1cc(OC)c2cc(cnc2c1)-c1ccncc1

InChI Key InChIKey=HBXDLZBPKJEWHZ-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50039655   

TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039655(5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...)
Affinity DataKi:  14nMAssay Description:Inhibition of PDGF-stimulated autophosphorylation of PDGF-receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039655(5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039655(5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of p56 lck kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039655(5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of erbB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50039655(5,7-Dimethoxy-3-pyridin-4-yl-quinoline | CHEMBL684...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Platelet-derived growth factor receptor tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed