BDBM50040359 CHEMBL145159::N-[1,3-Bis-cyclopropylmethyl-7-(4-methoxy-benzyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl]-4-methoxy-benzenesulfonamide

SMILES COc1ccc(Cn2c(NS(=O)(=O)c3ccc(OC)cc3)nc3n(CC4CC4)c(=O)n(CC4CC4)c(=O)c23)cc1

InChI Key InChIKey=IPORQBCLYQZQEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040359   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040359(CHEMBL145159 | N-[1,3-Bis-cyclopropylmethyl-7-(4-m...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of adenosine binding to A1 receptorof rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040359(CHEMBL145159 | N-[1,3-Bis-cyclopropylmethyl-7-(4-m...)
Affinity DataIC50:  2.20E+3nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 microM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed