BDBM50040377 2-(2-Propoxy-phenyl)-1,7-dihydro-purin-6-one::2-(2-Propoxy-phenyl)-1,9-dihydro-purin-6-one::CHEMBL42713::SK&F-96321::SK-96321

SMILES CCCOc1ccccc1-c1nc2nc[nH]c2c(=O)[nH]1

InChI Key InChIKey=PQTJTRTXCNZDFT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040377   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040377(2-(2-Propoxy-phenyl)-1,7-dihydro-purin-6-one | 2-(...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of phosphodiesterase 5AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50040377(2-(2-Propoxy-phenyl)-1,7-dihydro-purin-6-one | 2-(...)
Affinity DataEC50:  2.00E+3nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040377(2-(2-Propoxy-phenyl)-1,7-dihydro-purin-6-one | 2-(...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed