BDBM50040780 CHEMBL163958::cid_234512::spiro[9H-fluorene-9,4'-(tetrahydro-1'H-imidazole)]-2',5'-dione

SMILES O=C1NC(=O)C2(N1)c1ccccc1-c1ccccc21

InChI Key InChIKey=SCDXMQOKVWBFBD-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040780   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50040780(CHEMBL163958 | cid_234512 | spiro[9H-fluorene-9,4'...)
Affinity DataKi:  1.25E+5nMAssay Description:Binding affinity towards cytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50040780(CHEMBL163958 | cid_234512 | spiro[9H-fluorene-9,4'...)
Affinity DataEC50:  334nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1 R01 HL081062-01 Project Title: HTS for Identification of VLA-4 Allosteric Modulators (ML...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040780(CHEMBL163958 | cid_234512 | spiro[9H-fluorene-9,4'...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed