BDBM50040927 CHEMBL268441::N-(1,3-Dioxo-6-phenylamino-2,3-dihydro-1H-isoindol-5-yl)-N-phenyl-acetamide

SMILES CC(=O)N(c1ccccc1)c1cc2C(=O)NC(=O)c2cc1Nc1ccccc1

InChI Key InChIKey=HLLXEUNKQFCLRG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50040927   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040927(CHEMBL268441 | N-(1,3-Dioxo-6-phenylamino-2,3-dihy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040927(CHEMBL268441 | N-(1,3-Dioxo-6-phenylamino-2,3-dihy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PDGF-dependent autophosphorylation of PDGF-R in mouse BALB/c3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040927(CHEMBL268441 | N-(1,3-Dioxo-6-phenylamino-2,3-dihy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of EGF-dependent autophosphorylation of EGF-R in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase(Oryctolagus cuniculus (Rabbit))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040927(CHEMBL268441 | N-(1,3-Dioxo-6-phenylamino-2,3-dihy...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitory activity was determined against protein kinase A (PKA) of rabbitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed