BDBM50041220 1,2-bis(5-amidinobenzofuran-2-yl)ethane::2-(2-{5-[(E)-amino(imino)methyl]-1-benzofuran-2-yl}ethyl)-1-benzofuran-5-carboximidamide::2-(2-{5-[(Z)-amino(imino)methyl]-1-benzofuran-2-yl}ethyl)-1-benzofuran-5-carboximidamide::2-{2-[5-amino(imino)methylbenzo[b]furan-2-yl]ethyl}benzo[b]furan-5-yl-iminomethanamine::CHEMBL279962

SMILES NC(=N)c1ccc2oc(CCc3cc4cc(ccc4o3)C(N)=N)cc2c1

InChI Key InChIKey=YMOFSDWBUFAIRB-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50041220   

TargetCoagulation factor X(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50041220(1,2-bis(5-amidinobenzofuran-2-yl)ethane | 2-(2-{5-...)
Affinity DataKi:  570nMAssay Description:Inhibition of bovine factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50041220(1,2-bis(5-amidinobenzofuran-2-yl)ethane | 2-(2-{5-...)
Affinity DataKi:  4.17E+3nMAssay Description:Competitive reversible inhibition of bovine thrombin using alpha-N-benzoyl-DL-arginine-p-nitroanilide hydrochloride as substrate after 15 to 40 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlandular kallikrein(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50041220(1,2-bis(5-amidinobenzofuran-2-yl)ethane | 2-(2-{5-...)
Affinity DataKi:  9.53E+3nMAssay Description:Competitive reversible inhibition of porcine pancreatic kallikrein using alpha-N-benzoyl-DL-arginine-p-nitroanilide hydrochloride as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50041220(1,2-bis(5-amidinobenzofuran-2-yl)ethane | 2-(2-{5-...)
Affinity DataKi:  5.70E+5nMAssay Description:The compound was evaluated for inhibitory activity against bovine Factor XaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041220(1,2-bis(5-amidinobenzofuran-2-yl)ethane | 2-(2-{5-...)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041220(1,2-bis(5-amidinobenzofuran-2-yl)ethane | 2-(2-{5-...)
Affinity DataIC50:  100nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed