BDBM50041467 7-Chloro-4-hydroxy-3-phenyl-1H-quinolin-2-one::7-chloro-4-hydroxy-3-phenylquinolin-2(1H)-one::CHEMBL31661::L-698532

SMILES Oc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12

InChI Key InChIKey=RDXQSWLUXKUQSI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50041467   

TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50041467(7-Chloro-4-hydroxy-3-phenyl-1H-quinolin-2-one | 7-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50041467(7-Chloro-4-hydroxy-3-phenyl-1H-quinolin-2-one | 7-...)
Affinity DataIC50:  170nMAssay Description:Compound was evaluated for its ability to displace [3H]-L-689,560 from rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50041467(7-Chloro-4-hydroxy-3-phenyl-1H-quinolin-2-one | 7-...)
Affinity DataIC50:  170nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed