BDBM50041550 CHEMBL3358413

SMILES Fc1ccc(cc1)S(=O)(=O)N1C(C2CC2)C2(CCS(=O)(=O)CC2)c2cc(ccc12)C(=O)NCc1ncc(Cl)cc1C(F)(F)F

InChI Key InChIKey=XHHOMZJUDICMLT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50041550   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50041550(CHEMBL3358413)
Affinity DataIC50:  3.30nMAssay Description:Antagonist activity against human GnRH receptor expressed in CHO cells by IP-one HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50041550(CHEMBL3358413)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of buserelin-induced response preincubated for 20 mins fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50041550(CHEMBL3358413)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of LHRH-induced response preincubated for 20 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50041550(CHEMBL3358413)
Affinity DataIC50:  3.30nMAssay Description:Antagonist activity against human GnRH receptor expressed in CHO cells by IP-one HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed