BDBM50042205 1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione::CHEMBL287129

SMILES CCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccccc1

InChI Key InChIKey=CLFCOXMMCBVJJB-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50042205   

TargetAdenosine receptor A2b(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50042205(1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  19nMAssay Description:Inhibition of [3H]-ZM-241,385 binding to human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Pharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50042205(1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  150nMAssay Description:Binding affinity at Adenosine A1 receptor in rat brain cortical membrane using [3H]-N6-R-phenylisopropyladenosine (R-PIA) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Pharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50042205(1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  150nMAssay Description:Inhibition of [3H]-CCPA binding to rat adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50042205(1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  950nMAssay Description:Inhibition of [3H]-PSB-11 binding to human Adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50042205(1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity against Adenosine A2 receptor in rat striatal membranes using [3H]5'-(N-ethylcarboxamido)-adenosine (NECA) as the ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50042205(1-Ethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of [3H]-MSX-2 binding to rat adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed