BDBM50042625 (E)-(3R,5S)-7-[2,4-Bis-(4-fluoro-phenyl)-5-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL331048::Sodium; 7-[2,4-bis-(4-fluoro-phenyl)-5-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate
SMILES CC(C)c1c(nc(-c2ccc(F)cc2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1
InChI Key InChIKey=TVIKMEWXHYDWEQ-LKWCPCFXSA-M
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50042625
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research (Niper)
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against 3-hydroxy-3-methylglutaryl-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Glaxo Group Research
Curated by ChEMBL
Glaxo Group Research
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against washed rat liver microsomal HMG-CoA reductase (HMGR)More data for this Ligand-Target Pair