BDBM50042932 CHEMBL3354996::US9512126, 17
SMILES Cc1cc(ccc1C(=O)NC1CC1)-c1cnc2c(NCCC(F)(F)F)cc(nn12)C1(CC1)c1cccc(F)c1F
InChI Key InChIKey=YEIIAQASSRCJDI-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50042932
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Mps1 (unknown origin) activity by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 0.700nMpH: 7.7 T: 2°CAssay Description:The human kinase Mps-1 phosphorylates a biotinylated substrate peptide. Detection of the phosphorylated product is achieved by time-resolved fluoresc...More data for this Ligand-Target Pair