BDBM50043019 CHEMBL3355029
SMILES O[C@H]1CC[C@@H](CC1)Oc1nc(nc2[nH]ncc12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2F)cc1
InChI Key
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50043019
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant SGK1 (unknown origin) expressed in U2OS cells by cellular activity assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.5nMAssay Description:Inhibition of SGK1 (unknown origin) assessed as substrate phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate incubated for 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 253nMAssay Description:Inhibition of mouse SGK1 in presence 500 uM presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...More data for this Ligand-Target Pair