BDBM50043362 1,8-Dihydroxy-10-[2-(3,4,5-trihydroxy-phenyl)-acetyl]-10H-anthracen-9-one::CHEMBL335405

SMILES Oc1cccc2C(C(=O)Cc3cc(O)c(O)c(O)c3)c3cccc(O)c3C(=O)c12

InChI Key InChIKey=HYUVUMMAOVZCFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043362   

Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043362(1,8-Dihydroxy-10-[2-(3,4,5-trihydroxy-phenyl)-acet...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043362(1,8-Dihydroxy-10-[2-(3,4,5-trihydroxy-phenyl)-acet...)
Affinity DataIC50:  2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed