BDBM50043493 CHEMBL313813::N,N-Diethyl-2-[2-oxo-5-pyridin-2-yl-3-(3-m-tolyl-ureido)-2,3-dihydro-benzo[e][1,4]diazepin-1-yl]-acetamide

SMILES CCN(CC)C(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2cccc(C)c2)C1=O)c1ccccn1

InChI Key InChIKey=JMPBEXMAAHRJQV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50043493   

TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043493(CHEMBL313813 | N,N-Diethyl-2-[2-oxo-5-pyridin-2-yl...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043493(CHEMBL313813 | N,N-Diethyl-2-[2-oxo-5-pyridin-2-yl...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043493(CHEMBL313813 | N,N-Diethyl-2-[2-oxo-5-pyridin-2-yl...)
Affinity DataIC50:  435nMAssay Description:Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043493(CHEMBL313813 | N,N-Diethyl-2-[2-oxo-5-pyridin-2-yl...)
Affinity DataIC50:  435nMAssay Description:Inhibition of ligand binding to Cholecystokinin type A receptor receptor from rat pancreatic tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed