BDBM50043663 CHEMBL3355551::US10392392, Example 8-55::US10875864, EX. 8-55::US9416132, 8-55
SMILES C[C@]1(O)CC[C@@H](CC1)Nc1ccn2ncc(-c3cccc(c3)C(F)(F)F)c2n1
InChI Key InChIKey=ITUYHNBWFITURV-RHDGDCLCSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50043663
Affinity DataIC50: 54nMT: 2°CAssay Description:These assays are set up in duplicate 50 ul volumes in white, flat bottom 96 well plates. Inhibitors are added to the solution of 1× kinase buff...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of Pim1 (unknown origin) using luciferase-luciferin based ATP detection reagent by Kinase-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 639nMAssay Description:Inhibition of Pim2 (unknown origin) using luciferase-luciferin based ATP detection reagent by Kinase-Glo assayMore data for this Ligand-Target Pair