BDBM50043676 6-[3-Fluoro-5-((S)-1-methoxy-1-methoxymethyl-propyl)-phenoxymethyl]-1-methyl-1H-quinolin-2-one::CHEMBL21651

SMILES CC[C@](COC)(OC)c1cc(F)cc(OCc2ccc3n(C)c(=O)ccc3c2)c1

InChI Key InChIKey=XYOCJTXGNAJTKG-HSZRJFAPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043676   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50043676(6-[3-Fluoro-5-((S)-1-methoxy-1-methoxymethyl-propy...)
Affinity DataIC50:  70nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50043676(6-[3-Fluoro-5-((S)-1-methoxy-1-methoxymethyl-propy...)
Affinity DataIC50:  45nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed