BDBM50043677 (S)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]-2-methoxy-butyric acid methyl ester::CHEMBL20599

SMILES CC[C@@](OC)(C(=O)OC)c1cc(F)cc(OCc2ccc3ccccc3c2)c1

InChI Key InChIKey=YOFHXPYZDXQNER-QHCPKHFHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043677   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50043677((S)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50:  330nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50043677((S)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50:  5nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed