BDBM50043681 4-[3-(1-Methyl-2-oxo-1,2-dihydro-quinolin-6-ylmethoxy)-phenyl]-tetrahydro-pyran-4-carboxylic acid ethyl ester::CHEMBL20749

SMILES CCOC(=O)C1(CCOCC1)c1cccc(OCc2ccc3n(C)c(=O)ccc3c2)c1

InChI Key InChIKey=OATBNTYOFYSQDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50043681   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50043681(4-[3-(1-Methyl-2-oxo-1,2-dihydro-quinolin-6-ylmeth...)
Affinity DataIC50:  70nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed