BDBM50044236 CHEMBL303339::Dimethyl-(R)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::R-(+)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine

SMILES CN(C)[C@@H]1CCc2ccc3[nH]ccc3c2C1

InChI Key InChIKey=HENBLLXAHPTGHX-LLVKDONJSA-N

Data  7 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50044236   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50044236(CHEMBL303339 | Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50044236(CHEMBL303339 | Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50044236(CHEMBL303339 | Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...)
Affinity DataKi:  15nMAssay Description:Binding affinity rat Dopamine receptor D2 expressed in CHO-K1 cells by [3H]U-86170 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50044236(CHEMBL303339 | Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...)
Affinity DataKi:  25nMAssay Description:In vitro binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50044236(CHEMBL303339 | Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]-spiperone from dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50044236(CHEMBL303339 | Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...)
Affinity DataKi:  228nMAssay Description:In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor beta expressed in CHO cells, by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50044236(CHEMBL303339 | Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...)
Affinity DataKi:  270nMAssay Description:In vitro binding affinity against cloned mammalian Dopamine receptor D3 expressed in CHO cells by, using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50044236(CHEMBL303339 | Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...)
Affinity DataIC50:  31nMAssay Description:In vitro binding activity against 5-hydroxytryptamine 1A receptor from homogenized rat brain, using [3H]8-OH-DPAT as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50044236(CHEMBL303339 | Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...)
Affinity DataIC50:  1.05E+3nMAssay Description:In vitro binding activity against dopamine receptor D2 from homogenized rat brain, using [3H]spiperone as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50044236(CHEMBL303339 | Dimethyl-(R)-6,7,8,9-tetrahydro-3H-...)
Affinity DataIC50:  2.04E+4nMAssay Description:In vitro binding activity against dopamine receptor D1 from homogenized rat brain, using [3H]SCH-23390 as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed