BDBM50044636 CHEMBL3309297

SMILES CC1(C)CC(=O)Nc2ccc(cc12)C(=O)NC[C@H]1CC[C@@H](CC1)\C=C\C(=O)NO

InChI Key InChIKey=RIHKXPFNMAZMOA-KTRQRASZSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50044636   

TargetHistone deacetylase 1(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044636(CHEMBL3309297)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044636(CHEMBL3309297)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of human HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044636(CHEMBL3309297)
Affinity DataIC50:  15nMAssay Description:Inhibition of human HDAC3 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044636(CHEMBL3309297)
Affinity DataIC50:  58nMAssay Description:Inhibition of human HDAC6 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044636(CHEMBL3309297)
Affinity DataIC50:  58nMAssay Description:Inhibition of human HDAC4 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044636(CHEMBL3309297)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human HDAC9 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandPNGBDBM50044636(CHEMBL3309297)
Affinity DataIC50:  6nMAssay Description:Inhibition of human HDAC8 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed