BDBM50044881 8-Chloro-4-methyl-1,4,5,6-tetrahydro-2H-benzo[f]quinolin-3-one::CHEMBL16456

SMILES CN1C(=O)CCC2=C1CCc1cc(Cl)ccc21

InChI Key InChIKey=ZGWJLFQGIWFVSR-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50044881   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50044881(8-Chloro-4-methyl-1,4,5,6-tetrahydro-2H-benzo[f]qu...)
Affinity DataKi:  17nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50044881(8-Chloro-4-methyl-1,4,5,6-tetrahydro-2H-benzo[f]qu...)
Affinity DataKi:  455nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
In DepthDetails Article
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50044881(8-Chloro-4-methyl-1,4,5,6-tetrahydro-2H-benzo[f]qu...)
Affinity DataIC50:  174nMAssay Description:In vitro inhibitory concentration required to inhibit Steroid 5-alpha-reductase type 1 in cultured Hs 68 human foreskin fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails Article
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50044881(8-Chloro-4-methyl-1,4,5,6-tetrahydro-2H-benzo[f]qu...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of DHT production in Hs 68 (human genital fibroblast) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50044881(8-Chloro-4-methyl-1,4,5,6-tetrahydro-2H-benzo[f]qu...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50044881(8-Chloro-4-methyl-1,4,5,6-tetrahydro-2H-benzo[f]qu...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration was tested on human 5-alpha reductase 1 isozymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed