BDBM50045107 CHEMBL1256978::GSK364735

SMILES Cn1c2cc(Cc3ccc(F)cc3)cnc2c(O)c(C(=O)NCCO)c1=O

InChI Key InChIKey=QWLNINWUBHHOLU-UHFFFAOYSA-N

Data  5 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50045107   

TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50045107(CHEMBL1256978 | GSK364735)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of recombinant HIV-1 integrase by strand-transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50045107(CHEMBL1256978 | GSK364735)
Affinity DataIC50:  3nMAssay Description:Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50045107(CHEMBL1256978 | GSK364735)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase by strand transfer scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50045107(CHEMBL1256978 | GSK364735)
Affinity DataKd:  26nMAssay Description:Displacement of [3H]GSK304649 from Human immunodeficiency virus 1 integrase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50045107(CHEMBL1256978 | GSK364735)
Affinity DataIC50:  11nMAssay Description:Displacement of 20 nM [3H]GSK304649 from Human immunodeficiency virus 1 integrase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50045107(CHEMBL1256978 | GSK364735)
Affinity DataIC50:  8nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed