BDBM50045393 (20RS)-8-ethyl-8-hydroxy-2,3,8,9,12,14-hexahydro-11H-[1,4]dioxino[3,2-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-9,12-dione::CHEMBL89887

SMILES CCC1(O)C(=O)OCc2c1cc1-c3nc4cc5OCCOc5cc4cc3Cn1c2=O

InChI Key InChIKey=HBLFZGVLEXZEFR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045393   

TargetDNA topoisomerase 1(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50045393((20RS)-8-ethyl-8-hydroxy-2,3,8,9,12,14-hexahydro-1...)
Affinity DataIC50:  470nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed