BDBM50045805 CHEMBL318852::N-Carboxymethyl-N-[2-(2,4-dichloro-phenyl)-ethyl]-2-(1H-indol-3-ylmethyl)-2-methyl-malonamic acid adamantan-2-yl ester

SMILES CC(Cc1c[nH]c2ccccc12)(C(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)N(CCc1ccc(Cl)cc1Cl)CC(O)=O

InChI Key InChIKey=UIISAWYHPZCXHX-VKXCFGGISA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50045805   

TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50045805(CHEMBL318852 | N-Carboxymethyl-N-[2-(2,4-dichloro-...)
Affinity DataKi:  12nMAssay Description:Tested for inhibition of [3H]-pCCK-8 specific binding to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(MOUSE)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50045805(CHEMBL318852 | N-Carboxymethyl-N-[2-(2,4-dichloro-...)
Affinity DataKi:  14nMAssay Description:Tested for binding affinity towards cholecystokinin type B receptor in mouse brain by displacement of [3H]-pBC264 radioligand (icv)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(RAT)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50045805(CHEMBL318852 | N-Carboxymethyl-N-[2-(2,4-dichloro-...)
Affinity DataKi:  28nMAssay Description:Tested for binding affinity towards cholecystokinin type B receptor in rat pancreas by displacement of [3H]-pCCK-8 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50045805(CHEMBL318852 | N-Carboxymethyl-N-[2-(2,4-dichloro-...)
Affinity DataKi:  1.22E+3nMAssay Description:Tested for binding affinity towards cholecystokinin type A receptor in rat pancreas by displacement of [3H]-pCCK-8 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50045805(CHEMBL318852 | N-Carboxymethyl-N-[2-(2,4-dichloro-...)
Affinity DataKi:  3.05E+3nMAssay Description:Tested for inhibition of [3H]-pCCK-8 specific binding to cholecystokinin type A receptor in guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed