BDBM50046187 CHEMBL3311228

SMILES O[C@@](Cn1cnnn1)(c1ccc(F)cc1F)C(F)(F)c1ccc(cn1)-c1ccc(OCC(F)(F)F)cc1

InChI Key InChIKey=IDUYJRXRDSPPRC-NRFANRHFSA-N

Data  4 IC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50046187   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046187(CHEMBL3311228)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of CYP3A4 in human hepatocytes using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046187(CHEMBL3311228)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of CYP3A4 in human hepatocyte microsomes using testosterone substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046187(CHEMBL3311228)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046187(CHEMBL3311228)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed