BDBM50046355 CHEMBL110898::{2-[2-(1-Formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-1-naphthalen-1-yl-2-oxo-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)NC(CCCNC(N)=N)C=O)c1cccc2ccccc12

InChI Key InChIKey=PLAJAOHXCUUQEL-NWZLQDFTSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50046355   

TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046355(CHEMBL110898 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  620nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046355(CHEMBL110898 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046355(CHEMBL110898 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  2.00E+4nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046355(CHEMBL110898 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046355(CHEMBL110898 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed