BDBM50046550 CHEMBL439122::Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI Key InChIKey=QHUWIYRYNYUDLJ-CDTCBKJLSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50046550   

TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50046550(CHEMBL439122 | Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-I...)
Affinity DataKi:  1nMAssay Description:Tested against neuropeptide Y2 receptors using SK-N-BE2 human neuroblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50046550(CHEMBL439122 | Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-I...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50046550(CHEMBL439122 | Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-I...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50046550(CHEMBL439122 | Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-I...)
Affinity DataKi:  200nMAssay Description:Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50046550(CHEMBL439122 | Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-I...)
Affinity DataKi:  200nMAssay Description:Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50046550(CHEMBL439122 | Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-I...)
Affinity DataKi:  261nMAssay Description:Tested against neuropeptide Y1 receptors using SK-N-MC human neuroblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50046550(CHEMBL439122 | Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-I...)
Affinity DataKi:  398nMAssay Description:Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50046550(CHEMBL439122 | Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-I...)
Affinity DataKi:  400nMAssay Description:Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50046550(CHEMBL439122 | Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-I...)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50046550(CHEMBL439122 | Tyr-Pro-Ser-Lys-[Aca]-Arg-His-Tyr-I...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed