BDBM50046656 2,6-Dimethyl-5-(2-methyl-pyridin-4-ylsulfanyl)-3H-quinazolin-4-one::CHEMBL350130

SMILES Cc1cc(Sc2c(C)ccc3nc(C)[nH]c(=O)c23)ccn1

InChI Key InChIKey=JXDJARWIPBCTJS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50046656   

TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046656(2,6-Dimethyl-5-(2-methyl-pyridin-4-ylsulfanyl)-3H-...)
Affinity DataKi:  39nMAssay Description:Inhibition of human Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046656(2,6-Dimethyl-5-(2-methyl-pyridin-4-ylsulfanyl)-3H-...)
Affinity DataKi:  66nMAssay Description:Inhibition of human Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046656(2,6-Dimethyl-5-(2-methyl-pyridin-4-ylsulfanyl)-3H-...)
Affinity DataKi:  240nMAssay Description:Inhibition of purified E. coli Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046656(2,6-Dimethyl-5-(2-methyl-pyridin-4-ylsulfanyl)-3H-...)
Affinity DataKi:  530nMAssay Description:Inhibition of purified E. coli Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed