BDBM50046841 CHEMBL357864::Morpholine-4-carboxylic acid {2-cyclohexyl-1-[1-(2,3-dihydroxy-5-methyl-1-naphthalen-2-ylmethyl-hexylcarbamoyl)-2-methyl-butylcarbamoyl]-ethyl}-amide

SMILES CCC(C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)N1CCOCC1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)[C@@H](O)[C@@H](O)CC(C)C

InChI Key InChIKey=KLNHCORKYXXGEP-JWEFNPAHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50046841   

TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046841(CHEMBL357864 | Morpholine-4-carboxylic acid {2-cyc...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046841(CHEMBL357864 | Morpholine-4-carboxylic acid {2-cyc...)
Affinity DataIC50:  68nMAssay Description:Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046841(CHEMBL357864 | Morpholine-4-carboxylic acid {2-cyc...)
Affinity DataIC50:  350nMpH: 6.0Assay Description:In vitro inhibition of partially purified human renin at pH 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed