BDBM50047499 1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)-propoxy]-phenyl}-3-pentyl-urea::CHEMBL296094

SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C

InChI Key InChIKey=MRSWFEPPCGEHKT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50047499   

TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047499(1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazo...)
Affinity DataIC50:  110nMAssay Description:Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047499(1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazo...)
Affinity DataIC50:  43nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047499(1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazo...)
Affinity DataIC50:  110nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047499(1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazo...)
Affinity DataIC50:  43nMAssay Description:Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed