BDBM50048873 1-Benzyl-4-[3-(3,4-dihydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL50029

SMILES C(CN1CCN(Cc2ccccc2)CC1)CC1=CCCc2ccccc12

InChI Key InChIKey=BURLNZFZEWVOBR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50048873   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50048873(1-Benzyl-4-[3-(3,4-dihydro-naphthalen-1-yl)-propyl...)
Affinity DataKi:  66nMAssay Description:Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50048873(1-Benzyl-4-[3-(3,4-dihydro-naphthalen-1-yl)-propyl...)
Affinity DataKi:  214nMAssay Description:Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50048873(1-Benzyl-4-[3-(3,4-dihydro-naphthalen-1-yl)-propyl...)
Affinity DataKi:  8.43E+3nMAssay Description:Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed